Opening a PRJZIP File

The PRJZIP file type is primarily associated with Maestro.

PRJZIP	File extension: PRJZIP
	File type:	Compressed Project

What is a PRJZIP file?

PRJZIP files mostly belong to Maestro by Schrödinger, LLC. Maestro is an all-purpose molecular modeling environment and the unified interface for all Schrödinger software. PRJZIP files are zipped versions of Maestro .PRJ projects. PRJZIP files can be opened directly with Maestro and are opened as temporary scratch projects. Once they are closed, any changes are discarded. Effectively this makes the .PRJZIP file read-only. Use the SaveAs command to save any changes to a project to a new file.

How can I open a PRJZIP file?

You need a suitable software like Maestro to open a PRJZIP file. You need a suitable software like Maestro from Schrödinger, LLC to open a PRJZIP file. Without proper software you will receive a Windows message "How do you want to open this file?" or "Windows cannot open this file" or a similar Mac/iPhone/Android alert. If you cannot open your PRJZIP file correctly, try to right-click or long-press the file. Then click "Open with" and choose an application. You can also display a PRJZIP file directly in the browser:. Just drag the file onto this browser window and drop it.

Online PRJZIP Text Viewer

Choose your .prjzip file to analyze

or drag and drop it here

Online File Viewer

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Trouble Opening a .PRJZIP File? These Steps Will Help

Because .PRJZIP files can originate from specialized applications, they aren't universally openable by standard software.

Identify the Source: If received from a computational chemist or molecular modeling workflow, it is likely a Compressed Project file for Schrödinger's Maestro.
Check the Header: Open the file in a hex viewer or text editor to inspect the first few bytes:
- "PK" (50 4B) indicates a standard ZIP archive container.
- Readable XML or JSON suggests a different, uncompressed project format.
Use the Original Software: Opening the file usually requires the original program, such as Schrödinger Maestro or a standard archive extractor; if uncertain, ask the sender.
Use this Webpage: Drag and drop your file into our viewer to detect the format, extract readable text/metadata, and preview when possible.

Technical Data for PRJZIP File Extension

File classification:

How to solve problems with PRJZIP files

Associate the PRJZIP file extension with the correct application.
Update your software that should actually open compressed projects. Because only the current version supports the latest PRJZIP file format. Search, therefore, e.g. on the Schrödinger, LLC manufacturer website after an available Maestro update.
To make sure that your PRJZIP file is not corrupted or virus-infected, get the file again and scan it with Google's virustotal.com.
Click here to open your .PRJZIP file online - secure, fast, and no downloads needed.