All about SRA Files

The SRA file type is primarily associated with sra-tools.

SRAFile Extension SRA
File extension: SRA
File type:  raw sequencing data file

What is an SRA file?

SRA files mostly belong to sra-tools. SRA files serve multiple roles. The primary use is to hold raw sequencing data in the Sequence Read Archive, managed with sra-tools from NCBI. Use the tool from this page for details on converting these files (for example, to FASTQ format) for analysis.
Other roles include:
  • Security risk assessment files generated by Java applications to evaluate system vulnerabilities.
  • Scrapbook files created with Scrapbook Factory Deluxe using a Microsoft Compound format to store mixed media notes.
  • Game save files such as Zelda 64 progress files, which may also serve as compressed Sega Saturn ROMs and work with emulators like Snes9x (Snes9x website).
  • FilExt.com notes: When handling an SRA file, first confirm its origin. If it holds biological sequencing data, use sra-tools to convert or view the data. For the other formats, use the corresponding proprietary application or check the file header using a hex editor.

    How do you open SRA files?

    You need a suitable software like sra-tools to open an SRA file. Without proper software you will receive a Windows message "How do you want to open this file?" or "Windows cannot open this file" or a similar Mac/iPhone/Android alert. If you cannot open your SRA file correctly, try to right-click or long-press the file. Then click "Open with" and choose an application. You can also display a SRA file directly in the browser:. Just drag the file onto this browser window and drop it.

    Online SRA Text Viewer

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    Programs that open and convert SRA files:

    1. sra-tools
      See the previous paragraphs to learn more about the main application. SRA files are often referred to as sra-tools data files because this type of file is primarily created or used by this software.
    2. PowerBuilder (Application) by Sybase

    Technical Data for SRA File Extension

    File classification:
    Data
    Related files:

    The following listing is compiled from the database produced by the 'Associate This!' program, selected data from the main FILExt database and file extension information submitted by users.

    ProgramID: ActivPackRas.Document
    EXEFile: %ProgramFiles%\ACTIVC~1\ACTIVP~1\CLIENT~1\ACTIVP~1.EXE %1

    ProgramID: NovaDevelopment.ScrapbookFactory.Craft
    EXEFile: %ProgramFiles%\Art Explosion\Scrapbook Factory\scrapbk.exe %1

    ProgramID: NovaDevelopment.ScrapbookFactory.Craft
    EXEFile: %ProgramFiles%\Nova Development\Scrapbook Factory\scrapbk.exe %1

    ProgramID: IdeaSoft.ScrapbooksPlus.Craft
    EXEFile: %ProgramFiles%\IdeaSoft\Scrapbooks Plus\scrapbk.exe

    ProgramID: NovaDevelopment.ScrapbookFactory.Craft
    EXEFile: %ProgramFiles%\Ideasoft\Scrapbooks Plus\scrapbk.exe

    ProgramID: NovaDevelopment.ScrapbookFactory.Craft
    EXEFile: %ProgramFiles%\SCRAPBOOK FACTORY DELUX\scrapbk.exe


    an sra raw sequencing data file is a special file format and should only be edited and saved with the appropriate software.

    How to solve problems with SRA files

    • Associate the SRA file extension with the correct application.
    • Update your software that should actually open raw sequencing data files. Because only the current version supports the latest SRA file format. Search, therefore, e.g. on the manufacturer website after an available sra-tools update.
    • To make sure that your SRA file is not corrupted or virus-infected, get the file again and scan it with Google's virustotal.com.
    • Click here to open your .SRA file online - secure, fast, and no downloads needed.
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    SRA file viewer SRA file description